How Midolam Works
Midazolam enhances the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that slows brain activity. This results in sedation, muscle relaxation, and reduced anxiety. Its fast action helps calm the nervous system quickly, making it particularly useful in procedural and short-term clinical use.
Dosage
Dosage depends on the patient’s age, medical condition, and the purpose of use (such as insomnia or procedural sedation). For short-term insomnia, low oral doses are usually taken shortly before bedtime. When used for medical procedures, dosing is strictly determined and administered by healthcare professionals. Patients should never self-adjust the dose.
Side Effects
Common side effects include drowsiness, dizziness, headache, and short-term memory loss. Some individuals may experience nausea, confusion, or slowed breathing. Serious side effects are uncommon but are more likely with misuse, high doses, or overdose.
Pregnancy & Breastfeeding
Midazolam is generally not recommended during pregnancy unless clearly necessary, as it may affect the unborn baby, particularly with repeated or high-dose use. The drug can pass into breast milk, so breastfeeding should be avoided or temporarily paused unless advised otherwise by a healthcare professional.
Storage
- Store at room temperature.
- Keep away from heat, light, and moisture.
- Do not use if the packaging is damaged or after the expiry date.
- Keep out of reach of children at all times.
UK Regulation
Midazolam is a Prescription Only Medicine (POM) in the United Kingdom. It is also classified as a Schedule 3 Controlled Drug under the Misuse of Drugs Regulations. Legal supply and use require a valid prescription and appropriate medical supervision.